Chem. Name
3,4’,5-trihydroxy-trans-stilbene;5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benznediol
（S.F）
Molecular Formula：C14H12O3
Molecular Weight：228.24
CAS Registry Number：501-36-0
Characteristic: White Fine Powder
（ASSAY）HPLC， 1HNMR ≥50% ≥90% ≥95% ≥98% ≥99%
Packing: 1kg/ aluminum foil with double platic bags insides.
5kg,15kg,25kg/paper drum with double platic bags insides.
Output: 200kg/Mo.(≥98%)
Function:
Resveratrol is an active component extracted from Huzhang(Polygonum cuspidatum) in China. It is an antioxidant phenol and a potent vasodilator that inhibits serum triglyceride synthesis, lipid peroxidation, and platelet aggregation.
It is extensively used for treatment of blood vessel disease such as atherosclerosis and hyperlipidemia. In addition, it has anti-virus and anti-inflammatory activity, can treat acute microbial infections and viral hepatitis, ect.
Microencapsulation
What is the Microencapsulation?
Microencapsulation is not a product, it is a process actually. There are many examples existing in natural, egg; seed etc. Cell is also example of microencapsulation in microcosm.
Microencapsulation is composed of core and shell.
Size: 1~250μm(CHP)
Core: active content
Shell: protect core from external atmosphere.
Why Microencapaulation?
Microencapaulation is not a new technique in Pharmaceuticals, but only a few companies who manufacture Microencapsulated resveratrol over the world.
The benefits of Microencapsulated resveratrol include:
★ Protection of unstable, sensitive materials from their environments prior to use.
★ Better processability (improving solubility, dispersibility, flowability)
★ Self-life enhancement by preventing degradative reactions
★ Controlled, sustained, or timed release
[Functional Coatings and Microencapsulation: A General Perspective; Swapan Kumar Ghosh]
Acetyl –resveratrol is called prodrug on medicinal chemistry. Hydroxyls are replaced by acetyls.
Resveratrol
Acetyl-resveratrol
Acetyl-resveratrol is more stable than trans-resveratrol. When absorbed, it returns to resveratrol under action of metabolism.
Dosage form varied from pill to capsule up to different requirements when use Acetyl-resveratrol as raw material.
Resveratrol is unstable because its Hydroxyls are active group when exposure to oxygen, light and heat. The purpose of acetylation is to inactivate Resveratrol before absorption.
Acetyl-resveratrol is soluble in water (but not resveratrol). Therefore, it can be widely used in cosmetic industry, pharmaceutics, food, beverage, health products.
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